“worst in class case.”
“(a) Does Seroxat have a capacity “to cause adverse effects consequent upon or following discontinuance (withdrawal) such as to prevent or make more difficult the ability of users to discontinue, withdraw from or remain free from taking”
“That does not mean that it may not be a step that could be taken at a later stage nor does it mean that, if so advised, the Defendant may not apply for summary judgment at some stage.”
“whether there are, or not, particular benefits associated with Seroxat will therefore not feature at trial and, as Foskett J ruled in March 2017, it is now far too late to expand the scope of the trial to include evidence of risks/benefits.”
“1. Is it appropriate in principle to assess whether the prescription only medicine Seroxat is defective pursuant tos.3 of the Consumer Protection Act 1987 by seeking to establish whether it is “worst in class” in that: a. it causes adverse effects on discontinuation which are (i) of a greater incidence (ii) a greater severity and (iii) a longer duration than the other medicines in the class; and that b. such adverse effects prevent or make more difficult the ability of users to discontinue, withdraw from or remain free from Seroxat than is the case with the other medicines in the class?”
“57 It must be made clear from the outset that it is not and has never been the Claimants’ case that a product can be shown to be defective within the CPA 1987 merely by identifying one negative and/or undesirable aspect of it whilst ignoring any advantages. It is a reductio ad absurdum on the part of the Defendant that fails to recognise the case being advanced by the Claimants. 58. Rather, there is in truth no inconsistency between the ‘comparative’ and ‘holistic’ approaches. The Claimants’ case is indeed inherently comparative; but it does not exist in a vacuum divorced from either the marketplace or clinical reality. Thus, what is being advanced herein is indeed a holistic approach, namely that whatever the benefits asserted by the Defendant for this product in these proceedings, they are outweighed by the risks and problems associated with DS, having regard to inter alia the existence of equally efficacious products which do not have those risks/problems.”
“we are not and have never said that Seroxat is demonstrably unsafe because it’s worst in class, as if all we ever have to do or ever have had to do was come to court and … show you that ..Seroxat is the worst performance, ergo it becomes worst in class, ergo it is unsafe.”
“we do very much - we are perfectly frank about this – recognise that our case is a shadow of its former self, and therefore we would have to give certain very strong advice to the clients and anyone who’s incurring any expense on their behalf.”
“They do not accept that it has become an unarguable case or that the claims could not succeed if the court in due course finds that the nature, severity and frequency of Discontinuation Symptoms associated with Seroxat was so marked and significant that the court could find the drug defective under the CPA on that basis alone (or in conjunction with inadequate warnings).”
“this is a situation where the Claimants were wrong, one might even say misguided, but their conduct was not cynical or otherwise highly unreasonable. There was a basis in the pleadings for the position they took. There were reasons, ultimately held not to be sufficient, but legitimate reasons for their understanding of the position following Mr Justice Foskett’s and your ladyship’s rulings.”